Management of youth psoriatic arthritis with etanercept: a case report Etanercept controls youth psoriatic arthritis

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29-Nov-1874.pdf
Published Dec 20, 2018
DOI: https://doi.org/10.18103/mra.v6i12.1874

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Claudio Roberto Bezerra-Santos
Associate Professor of Immunology, Department of Physiology and Pathology, Health Science Centre, Laboratory of Immunopharmacology, Federal University of Paraiba (UFPB), Joao Pessoa, Brazil
Esther Bastos Palitot
Professor of Dermatology, Head of Reference Service for Psoriasis, Federal University of Paraiba (UFPB), Medical Science Centre, LauroWanderley Hospital Ebserh/UFPB, Joao Pessoa, Brazil
Guilherme Bastos Palitot Brito
Resident Doctor, Federal University of Rio Grande do Norte (UFRN), Natal, Brazil.
Alessandra de Sousa Braz
Professor of Rheumatology, Spondyloarthritis Clinic, Federal University of Paraiba (UFPB), Medical Science Centre, LauroWanderley Hospital Ebserh/UFPB, Joao Pessoa, Brazil

Abstract

Psoriatic arthritis (PsA) is an immune-mediated inflammatory disease of the skin and joints still poorly understood in pediatric patients. It has been reported a case report of PsA in a male infant patient in Paraiba state, Northeast Brazil. The goal of this study was describing a rare case of juvenile PsA and its management upon using classical and biologic treatment based on the drug etanercept. The patient was diagnosed with scales on the scalp, knees and other parts of the body and joint inflammation besides social behavior deficit since he was aged 5. Classical therapy to PsA including acitretrin and topical glucocorticoids did not ameliorate the illness symptoms. Then, the patient received the anti-TNF-α drug etanercept used to treat moderate to severe psoriasis and juvenile rheumatoid arthritis. Before the week 16 of the treatment was observed a strong remission of the symptoms which is related to the inhibition of the inflammatory response into skin and joints. Besides no side effects was observed during etanercept administration. This study indicates that anti-TNF-α therapy might be used to treat immune-mediated inflammation likely to PsA in pediatric patients.  


Keywords: Juvenile patient, psoriatic arthritis, biologic therapy

Keywords: Juvenile patient, psoriatic arthritis, biologic therapy

Article Details

How to Cite
BEZERRA-SANTOS, Claudio Roberto et al. Management of youth psoriatic arthritis with etanercept: a case report. Medical Research Archives, [S.l.], v. 6, n. 12, p. 1-7, dec. 2018. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/1874>. Date accessed: 19 apr. 2024. doi: https://doi.org/10.18103/mra.v6i12.1874.
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Issue
Vol 6 No 12 (2018): Vol.6 Issue 12, December 2018
Section
Case Reports

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